l Umubare wa Cas: 171596-29-5 Inzira ya molekulari: C₂₂H₁₉N₃O₄
| Ingingo yo gushonga | > 193 ° C. |
| Ubucucike | DMF: 25 mg / ml DMF: PBS (pH 7.2) (1: 1): 0.5 mg / ml DMSO: 20 mg / ml |
| ububiko bwa temp | -20 ° C. |
| gukemura | DMF: 25 mg / ml DMF: PBS (pH 7.2) (1: 1): 0.5 mg / ml DMSO: 20 mg / ml |
| ibikorwa byiza | [α] / D +68 kugeza + 78 °, c = 1 muri chloroform-d |
| Kugaragara | Umweru Kuri Off-White Solid |
| Isuku | ≥98% |
.Ingaruka zo ni ukuruhura imitsi yamaraso no kongera amaraso muri corpus cavernosum.Uburyo bwibikorwa ni muburyo bwo guhagarika ibikorwa bya cGMP yihariye ya fosifisiyose ya 5 (PDE5).PDE5 itesha agaciro cGMP muri corpus cavernosum iherereye hafi yimboro.Kubwibyo, tadalafi itera kwiyongera kwa cGMP itera kurushaho kunoza imitsi neza no kwiyongera kwamaraso muri corpus cavernosum.Ubushakashatsi bumwe na bumwe bw’ubuvuzi bwerekanaga kandi ko bushobora kunoza imikorere ya endoteliya ku bagabo bafite ibyago byinshi by’umutima n’imitsi ndetse bikanagabanya ibimenyetso by’inkari by’inkari kugeza kuri hyperplasia nziza.
analgesic, uptake blocker, mu-opiod reseptor agonist.Fosifodiyesterase 5 inhibitor.ikoreshwa mu kuvura imikorere mibi.
ni itandukanye muburyo butandukanye na sildenafil na vardenafil.Ihita yihuta cyane kandi igera hejuru (378 μg / L nyuma ya 20 mg ya dose) nyuma yamasaha 2, ikerekana igice kirekire cyubuzima bwamasaha 17.5.Ihinduranya kandi n'umwijima (CYP3A4).Ikigaragara ni uko imiti ya farumasi idaterwa n'inzoga cyangwa gufata ibiryo cyangwa ibintu nka diyabete cyangwa imikorere mibi y'umwijima cyangwa impyiko.
