Acarbose Cas numero: 56180-94-0 Imiterere ya molekulari ： C25H43NO18

Ibisobanuro bigufi:

Numero ya Cas: 56180-94-0

Izina ryimiti ： Acarbose

Inzira ya molekulari ：C25H43NO18

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Ibicuruzwa birambuye

Ibicuruzwa

Synonyme

Precos
Precose
Prandase
ACARBOSE
Glucobay
bay-g5421
Ascarbose
Acarbose API
Acarbose, 98%
Acarbose Hydrate
Bay g 5421 ： Glucobay
Acarbose (Acarbosum)
4) -OaD-glucopyranosyl- (1®
-alpha-d-glucopyranosyl- (1-4) -
AMylostatin J, Bay g 5421, alpha-GHI
(2R, 3R, 4R, 5S, 6R) -5 - ((2R, 3R, 4R, 5S, 6R) -5-
Acarbose fom Actinoplanes sp.ca.100 FIP-AIU / mg
O-4,6-DIDEOXY-4 - [[[1S- (1A, 4A, 5BETA, 6A)] - 4,5,6-TRIHYDROXY-3-
d-glucose, o-4,6-dideoxy-4 - (((1s- (1-alfa, 4-alfa, 5-beta, 6-alfa)) - 4,5,6-trihyd
roxy-3- (hydroxymethyl) -2-cyclohexen-1-yl) amino) -alpha-d-glucopyranosyl- (1-4) -o
4 ", 6" -Dideoxy-4 "- ([1S] - [1,4,6 / 5] -4,5,6-trihydroxy-3-hydroxymethyl-2-yclohexenylamino) -maltotriose
D-Glucose, O-4,6-dideoxy-4 - [[(1S, 4R, 5S, 6S) -4,5,6-trihydroxy-3- (hydroxyMethyl) -2-cyclohexen-1-yl] aMino] -aD-glucopyranosyl- (1®
O-4,6-Dideoxy-4 - [[ -glucopyranosyl- (1-4) -O-α-D-glucopyranosyl- (1-4) -D-Glucose
4-O- [4-O- [4 - [[((1S, 4R, 5S, 6S) -4,5,6-Trihydroxy-3- , 6-dideoxy-α-D-glucopyranosyl] -α-D-glucopyranosyl] -D-glucopyranose
D-Glucose, O-4,6-dideoxy-4 - [[(1S, 4R, 5S, 6S) -4,5,6-trihydroxy-3- (hydroxymethyl) -2-cyclohexen-1-yl] amino] -α-D-glucopyranosyl- (1 → 4) -O-α-D-glucopyranosyl- (1 → 4) -
O-4,6-Dideoxy-4 - [[[1S- (1a, 4a, 5,6a)] - 4,5,6-trihydroxy-3- (hydroxymethyl) -2-cyclohexen-1-yl] amino] -aD-glucopyranosyl- (1-4) -OaD-glucopyranosyl- (1-4) -D-glucose
O-4，6-Dideoxy-4 - [[[1S (1α ， 4α ， 5β ， 6α -) - 4，5，6-trihydrDxy-3- (hydroxymethyl) -2-cyclohexen -1 α-D-glucopyranosyl- (1 → 4) -O-α-D-ducopyranosyl- (1 → 4) -D-glucose
O-4,6-Dideoxy-4 - [[1S- -α-D-glucopyranosyl- (1-4) -O-α-D-glucopyranosyl- (1-4) -D-glucose
O-4,6-Dideoxy-4 - [[[1S- (1a, 4a, 5b, 6a)] - 4,5,6-trihydroxy-3- (hydroxymethyl) -2-cyclohexen -1 -aD-glucopyranosyl- (1-4) -OaD-glucopyranosyl- (1-4) -D-gluco-
se
D-Glucose, O-4,6-dideoxy-4 - [[4,5,6-trihydroxy-3- (hydroxymethyl) -2-cyclohexen-1-yl] amino] -α-D-glucopyranosyl- (1 → 4) -O-α-D-glucopyranosyl- (1 → 4) -, [1S- (1α, 4α, 5β, 6α)] -
O-4,6-DIDEOXY-4 - [[[1S- (1A, 4A, 5BETA, 6A)] - 4,5,6-TRIHYDROXY-3- -ALPHA-D-GLUCOPYRANOSYL- (1-4) -O-ALPHA-D-GLUCOPYRANOSYL- (1-4) -D-GLUCOSE
5- [5- [3,4-DIHYDROXY-6-METHYL-5 - [[4.5,6 OXY-3,4-DIHYDROXY-6- (HYDROXYMETHYL) OXAN-2-YL] OXY-6- (HYDROXYMETHYL) OXANE-2,3,4-TRIOL

Ibicuruzwa byihariye

Ingingo yo gushonga	165-170 ° C.
Ubucucike	1.4278 (igereranya)
ububiko bwa temp	Ikirere cyinjiza, Ubushyuhe bwicyumba 2-8 ° C.
gukemura	Kubora cyane mumazi, gushonga muri methanol, muburyo budashonga muri methylene chloride.
ibikorwa byiza	N / A.
Kugaragara	Kuruhande rwera
Isuku	≥97%

Ibisobanuro

Acarbose, igoye ya oligosaccharide yitandukanije na Actinoplanes, ngo ni ingirakamaro nk'ubuvuzi buvura diyabete.Muguhagarika alpha-glucosidase, acarbose itinda metabolisiyumu ya karubone ya hydrata mu nzira ya gastrointestinal kandi igahindura impinduka mubiryo byatewe nisukari yamaraso.

Koresha

Acarbose ni pseudo-oligosaccharide hamwe na terminal C7-cyclitol yatanzwe muri 1975 na Bayer.Acarbose ni igice cyurwego rwa amylostatine rwakozwe nubwoko bwa Actinoplanes na Streptomyces.Acarbose ikora nka inhibitor ikomeye ya α-glucosidase na sakarase.Kuva mu 1990, acarbose yakoreshejwe mu kuvura indwara ya diyabete yo mu bwoko bwa 2.