Numero ya Cas: 1115-70-4 Inzira ya molekulari: C4H11N5

Ibicuruzwa

Numero ya Cas: 1115-70-4 Inzira ya molekulari: C4H11N5

Ibisobanuro bigufi:

Numero ya Cas: 1115-70-4
Izina ryimiti:
Inzira ya molekulari: C4H11N5
Synonyme: Hydrochloride, Glucophage, nibindi


Ibicuruzwa birambuye

Ibicuruzwa

ibicuruzwa

Ingingo yo gushonga 233-236 ℃
Ubucucike 1.48 g / cm³
ububiko bwa temp 15-30 ℃
gukemura Gushonga mumazi, gushonga muri Ethanol, no kudashonga muri chloroform na benzene.
ibikorwa byiza Impamyabumenyi +25.7 (C = 1, amazi)
Kugaragara ifu ya kirisiti yera

ibicuruzwa farumasi

Uburyo bwa farumasi ya farumasi ntabwo bwumvikana neza.Birazwi ko ikora byibuze ku mwijima, igabanya gluconeogenezesi (ni ukuvuga umusaruro wa glucose) no kugabanya insuline.Ubushakashatsi bumwe bwerekanye ko bushobora gukora AMP ikora protein kinase (AMPK), ikaba ari bumwe mu buryo bwingenzi bwo guhagarika umwijima gluconeogenez no kunoza insuline mu nzira yo kwanduza insuline.AMPK, nka protein kinase, igira uruhare runini ntabwo ari inzira yerekana ibimenyetso bya insuline gusa, ahubwo no muburyo rusange bwo kuringaniza ingufu hamwe na glucose hamwe na metabolism.Ubushakashatsi bw’inyamaswa n’ubushakashatsi bw’amavuriro bwerekanye ko bushobora gutera impinduka zikomeye mu bigize mikorobe ya fecal muri diyabete, idashobora kugira uruhare gusa mu gusohora n’ingaruka za glucagon nka peptide-1 (GLP-1), ariko kandi bikerekana ko bizamura insuline. , nimwe muburyo bukomeye bwingaruka za diyabete yo mu bwoko bwa 2.

gukoresha ibicuruzwa

Iki gicuruzwa kigomba gukoreshwa mukigero gito kandi kikiyongera buhoro buhoro ukurikije uko umurwayi ameze.Igipimo cyambere cyibicuruzwa (ibinini bya hydrochloride) mubisanzwe ni garama 0,5, kabiri kumunsi;Cyangwa garama 0,85, rimwe kumunsi;Fata amafunguro.

Imikoreshereze n'imikoreshereze

Iki gicuruzwa kigomba gukoreshwa mukigero gito kandi kikiyongera buhoro buhoro ukurikije uko umurwayi ameze.Igipimo cyambere cyibicuruzwa (ibinini bya hydrochloride) mubisanzwe ni garama 0,5, kabiri kumunsi;Cyangwa garama 0,85, rimwe kumunsi;Fata amafunguro.

Metformin

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  • Ibikurikira:

  • Andika ubutumwa bwawe hano hanyuma utwohereze