Florfenicol Cas numero: 73231-34-2 Imiterere ya molekulari ： C12H14Cl2FNO4S
2,2-dichloro-n - [(1r, 2s) -3-fluoro-1-hydroxy-1- (4-methylsulfonylphenyl) propan-2-yl] acetamide
AQUAFEN FLORFENICOL NUFLOR
[r- (r *, r *)] - n- [1- (fluoromethyl) -2-hydroxy-2- (4- (methyllsory
[R- (R *, S *)] - 2,2-DICHLORO-N- [1- (FLUOROMETHYL) -2-HYDROXY-2- [4-
SCH-25298
(r- (r *, s *)) - methyleste
2,2-dichloro-n- (1- (fluoromethyl) -2-hydroxy-2- (4- (methylsulfonyl) fenyl) Ethyl
4- (2 - ((dichloroacetyl) amino) -3-fluoro-1-hydroxypropyl) -benzenesulfonicaci
Florfeniol
FLUPROFEN
Fluorothiamphenicol
Sch-25298, Aquafen
Acetamide, 2,2-dichloro-N- (1S, 2R) -1- (fluoromethyl) -2-hydroxy-2-4- (methylsulfonyl) fenilethyl-
2,2-Dichloro-N - [(1S, 2R) -1- (fluoromethyl) -2-hydroxy-2- [4-
Aquaflor
Aquafen, Nuflor, SCH-25298, [R- (R *, S *)] - 2,2-Dichloro-N- [1- (fluoromethyl) -2-hydroxy-2- acetamide
2,2-Dichloro-N- (1- (fluoromethyl) -2-hydroxy-2- (4- (methylsulfonyl) fenyl) Ethyl) acetamide
2,2-Dichloro-N - [(1R, 2S) -3-fluoro-1-hydroxy-1- (4-methylsulfonylphenyl) propan-2-yl] acetamide
| Ingingo yo gushonga | 153 ° |
| Ubucucike | 1.451 ± 0.06 g / cm3 (Byahanuwe) 1.1782 (igereranya) |
| ububiko bwa temp | 2-8 ° C. |
| gukemura | Gukemura muri Ethanol kugeza kuri 25mM no muri DMSO kugeza 100mM |
| ibikorwa byiza | N / A. |
| Kugaragara | Umweru Kuri Off-White |
| Isuku | ≥98% |
Florfenicol ni antibiyotike ya fluor yagutse kandi ikomoka kuri thiamphenicol (Ingingo No 21357).Ifite imbaraga zo kurwanya ivuriro ry’abantu ryitwa bacteri enteric, harimo E. coli, Klebsiella, Enterobacter, Citrobacter, P. mirabilis, na Salmonella (MIC50s = 6.3-12.5 μg / ml).Florfenicol irakora kandi mukurwanya ivuriro rya bovine na porcine zitandukanye zandurira mu myanya y'ubuhumekero, harimo P. multocida, A. pleuropneumoniae, na B. bronchiseptica (MIC50s = 0,25-4 μg / ml).Irabuza ibikorwa byo kwimura peptidyl muri 70S ribosomes yitandukanije na E. coli iyo ikoreshejwe kuri mM 1.Imiti irimo florfenicol yakoreshejwe mu kuvura indwara z’ubuhumekero zanduza inka.
Nubwoko bwa antibacterial.Ikoreshwa nk'imiti igabanya ubukana bw'amatungo mu kuvura indwara za bagiteri z'ingurube, inkoko n'amafi.Ifite akamaro gakomeye mu kuvura indwara zanduza ingurube, inkoko n'amafi biterwa na bagiteri zoroshye, cyane cyane mu kuvura indwara z’ubuhumekero n'indwara zo mu nda.
